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Hot Products
  • AST2818 mesylate

    AST2818 mesylate

    R190306
    CAS NO.:2130958-55-1Product Name:AST2818 mesylateSynonyms:EINECS:Molecular Formula:C₂₉H₃₅F₃N₈O₅SMolecular Weight:664.70
  • Sugammadex sodium (Synonyms: Org25969)

    Sugammadex sodium (Synonyms: Org25969)

    R11425
    Sugammadex (Org 25969, tradename Bridion) is an agent for reversal of neuromuscular blockade by the agent rocuronium in general anaesthesia. It is the first selective relaxant binding agent (SRBA).
  • Erdafitinib (Synonyms: JNJ-42756493)

    Erdafitinib (Synonyms: JNJ-42756493)

    R910183
    Erdafitinib (JNJ-42756493) is a potent and orally available FGFR family inhibitor; inhibits FGFR1/2/3/4 with IC50s of 1.2, 2.5, 3.0 and 5.7 nM, respectively. 
  • Selitrectinib (LOXO-195)/CAS:1350884-56-8

    Selitrectinib (LOXO-195)/CAS:1350884-56-8

    R12008
    Selitrectinib (LOXO-195) is a next-generation TRK kinase inhibitor (TKI), with IC50s of 0.6 nM, <2.5 nM for TRKA and TRKC respectively.  CAS:1350884-56-8 is the racemic modification.
  • Deoxynivalenol

    Deoxynivalenol

    R11198
    Vomitoxin, also known as deoxynivalenol (DON), is a type B trichothecene, an epoxy-sesquiterpenoid. This mycotoxin occurs predominantly in grains such as wheat, barley, oats, rye, and maize, and less
  • Eliglustat hemitartrate (Synonyms: Genz-112638; Eliglustat tartrate)

    Eliglustat hemitartrate (Synonyms: Genz-112638; Eliglustat tartrate)

    R11057
    Eliglustat tartrate (Genz-112638), a specific inhibitor of glucosylceramide synthase, is under development as an oral substrate reduction therapy for Gaucher disease type 1 (GD1).
  • Anamorelin ; RC-1291

    Anamorelin ; RC-1291

    R11015
    Anamorelin(RC1291; ONO-7643) is a synthetic orally active ghrelin receptor agonist which is under development for the management of non-small lung cancer associated cachexia/anorexia.
  • Eliglustat (Synonyms: Genz 99067)

    Eliglustat (Synonyms: Genz 99067)

    R11006
    Eliglustat (Tartrate) inhibits glucosylceramide synthase(GCS),thus reducing the load of glucosylceramide influx into the lysosome.
  • Tenofovir Alafenamide (GS-7340)

    Tenofovir Alafenamide (GS-7340)

    R10583
    Tenofovir alafenamide (GS-7340) is an investigational oral prodrug of Tenofovir. Tenofovir is a HIV-1 nucleotide reverse transcriptase inhibitor. 
  • GFT505; elafibranor E

    GFT505; elafibranor E

    R10330
    Elafibranor is a PPARα/δ agonist with EC50s of 45 and 175 nM, respectively. 
  • AKT inhibitor VIII (AKTI-1/2)

    AKT inhibitor VIII (AKTI-1/2)

    R10014
    CAS NO.:612847-09-3Product Name:1-(1-(4-(6-Phenyl-1H-imidazo[4,5-g]quinoxalin-7-yl)benzyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-oneSynonyms:EINEC:Molecular Formula:C34H29N7OMolecular Weight:551.64
  • PF 04691502

    PF 04691502

    R10013
    PF-04691502 is an ATP-competitive PI3K(α/β/δ/γ)/mTOR dual inhibitor with Ki of 1.8 nM/2.1 nM/1.6 nM/1.9 nM and 16 nM in cell-free assays, little activity against either Vps34, AKT, PDK1, p70S6K, MEK,
  • Allitinib tosylate (Synonyms: AST-1306 (TsOH))/897383-62-9 Free base

    Allitinib tosylate (Synonyms: AST-1306 (TsOH))/897383-62-9 Free base

    R10006
    AST-1306 is a novel irreversible inhibitor of EGFR and ErbB2 with IC50 of 0.5 nM and 3 nM, also effective in mutation EGFR T790M/L858R, more potent to ErbB2-overexpressing cells, 3000-fold selective f
  • AT406 (SM-406, ARRY-334543)

    AT406 (SM-406, ARRY-334543)

    R10005
    AT-406 is an orally bioavailable inhibitor of IAP family of proteins with potential apoptotic inducing and antineoplastic activity. AT-406 selectively inhibits the biological activity of IAP proteins,
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